Evaluation of Repigmentation with Cultured Melanocyte Transplantation (CMT) Compared with Non-Cultured Epidermal Cell Transplantation in Vitiligo at 12th Week Reveals Better Repigmentation with CMT
نویسندگان
چکیده
منابع مشابه
Repigmentation of vitiligo with autologous blister-induced epidermal grafts.
Treatment of vitiligo can sometimes be difficult and disappointing. PUVA treatments give fairly good results. However, acral regions like the hands or feet or areas over bony prominences like the elbow, are resistant to PUVA. Blister-induced epidermal grafts have been used to repigment vitiligo skin. This study was carried out on patients with vitiligo areas unresponsive to either PUVA treatmen...
متن کاملNon-cultured autologous melanocytes of outer root sheath and bulge area transplantation for repigmentation of the stable generalized vitiligo patches: a pilot study
Background: Different modalities have been tried in order totreat stable vitiligo. Culturing melanocytes is time consumingand expensive. Therefore, new methods using autologousmelanocytes are sought. We aimed to compare the mixed nonculturedautologous melanocytes of the outer root sheath andthe bulge area of hair follicle transplantation plus dermabrasionwith dermabrasion alone in stable genera...
متن کاملVitiligo Repigmentation: What’s New?
Vitiligo is a relatively common acquired skin disorder, characterized by the progressive loss of melanocytes, which results in white patches. Classically, vitiligo’s treatments have been considered unsatisfactory and challenging. Recent advances in the knowledge of vitiligo’s pathogenesis have contributed to find better therapeutic options, so that at present many patients find a solution for d...
متن کاملEvaluation of treatment response to autologous transplantation of noncultured melanocyte/keratinocyte cell suspension in patients with stable vitiligo*
BACKGROUND Vitiligo is a chronic disease characterized by the appearance of achromic macules caused by melanocyte destruction. Surgical treatments with melanocyte transplantation can be used for stable vitiligo cases. OBJECTIVES To evaluate treatment response to the autologous transplantation of noncultured epidermal cell suspension in patients with stable vitiligo. METHODS Case series stud...
متن کاملUpdate on skin repigmentation therapies in vitiligo.
Treatment for vitiligo is difficult and prolonged. Nevertheless, at present considerable knowledge accumulated during several decades on the pathogenic mechanisms, revealed important clues for designing new strategies to improve vitiligo depigmentation. With available medical therapies, high repigmentation percentages mostly on facial and neck lesions are achieved, although they are less effect...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2015
ISSN: 0022-202X
DOI: 10.1038/jid.2015.178